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avinashkarkada/README.md

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About Me

I am a Bioinformatics Engineer at the Johns Hopkins School of Medicine.

My work sits at the intersection of bioinformatics, computational biology, immunology, and structural biology. I build and improve workflow and analysis pipelines, work with large-scale sequencing data, and use computational methods to study antibodies, epitopes, proteins, and biological systems.

I currently work on

  • PhIP-Seq antibody-profiling investigating influence of microbial dysbiosis on humoral immunity in early-onset, late-onset colorectal cancer, and polyp/healthy control cohorts.
  • Developing and maintaining computational pipelines for InFlux, a highly multiplexed NGS-based influenza A neutralization assay, analyzing samples to profile humoral immunity across diverse patient cohorts.

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  1. Influx_pipeline Influx_pipeline Public

    Influenza Neutralization Assay Pipeline (InFlux)

    Python

  2. Influenza_Antigenic_Cartography Influenza_Antigenic_Cartography Public

    Antigenic Cartography Mapping for H1N1 and H3N2

    Python

  3. PhIP-Seq-Pipeline-Installer PhIP-Seq-Pipeline-Installer Public

    These are the scripts developed for the Larman Lab which help new users install the PhIP-seq pipeline and its dependencies. This also installs Phipmake and ARscore dependencies.

    Shell

  4. drydock drydock Public

    Python

  5. GROMACS-COLAB GROMACS-COLAB Public

    Contains gromacs notebooks for MD simulations.

    Jupyter Notebook 5 1