Ensembl Anno

Ensembl Anno is a modular genome annotation framework developed by Ensembl.

It provides a single wrapper (ensembl_anno.py) that orchestrates a complete genome annotation workflow, including:

• Repeat annotation
• Simple feature annotation
• Small non-coding RNA annotation
• Transcriptomic evidence generation
• Protein homology annotation
• Gene set finalisation
• Optional loading into an Ensembl Core database

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Documentation

Full documentation is available at

https://ensembl.github.io/ensembl-anno/

The documentation contains

• Installation
• Configuration
• Pipeline overview
• Running the wrapper
• Examples
• Individual analysis modules
• API reference

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Quick start

python ensembl_anno.py \
    --genome_file genome.fa \
    --output_dir output \
    --run_full_annotation