diff --git a/setup.py b/setup.py
index eab9a38..e0bb57d 100644
--- a/setup.py
+++ b/setup.py
@@ -57,7 +57,7 @@ def has_uv() -> bool:
         "tqdm",
         "rdkit",
         "py3Dmol",
-        "openbabel-wheel",
+        "openbabel>=3.2.0",
         "boltz[cuda]==2.2.1",
         "freesasa",
     ],