diff --git a/src/binding.cc b/src/binding.cc
index bf6a44ec3b..6454d68eb0 100644
--- a/src/binding.cc
+++ b/src/binding.cc
@@ -152,8 +152,30 @@ bool v8__V8__Dispose() { return v8::V8::Dispose(); }
 
 void v8__V8__DisposePlatform() { v8::V8::DisposePlatform(); }
 
-v8::Isolate* v8__Isolate__New(const v8::Isolate::CreateParams& params) {
-  return v8::Isolate::New(params);
+v8::internal::IsolateGroup* v8__IsolateGroup__GetDefault() {
+  return make_pod<v8::internal::IsolateGroup*>(v8::IsolateGroup::GetDefault());
+}
+
+bool v8__IsolateGroup__CanCreateNewGroups() {
+  return v8::IsolateGroup::CanCreateNewGroups();
+}
+
+v8::internal::IsolateGroup* v8__IsolateGroup__Create() {
+  return make_pod<v8::internal::IsolateGroup*>(v8::IsolateGroup::Create());
+}
+
+void v8__IsolateGroup__DESTRUCT(v8::IsolateGroup* self) {
+  self->~IsolateGroup();
+}
+
+bool v8__IsolateGroup__EQ(const v8::IsolateGroup& self,
+                          const v8::IsolateGroup& other) {
+  return self == other;
+}
+
+v8::Isolate* v8__Isolate__New(const v8::IsolateGroup& group,
+                              const v8::Isolate::CreateParams& params) {
+  return v8::Isolate::New(group, params);
 }
 
 void v8__Isolate__Dispose(v8::Isolate* isolate) { isolate->Dispose(); }
diff --git a/src/isolate.rs b/src/isolate.rs
index 91757846da..58cf14c5a5 100644
--- a/src/isolate.rs
+++ b/src/isolate.rs
@@ -31,6 +31,7 @@ use crate::FixedArray;
 use crate::Function;
 use crate::FunctionCodeHandling;
 use crate::HandleScope;
+use crate::IsolateGroup;
 use crate::Local;
 use crate::Message;
 use crate::Module;
@@ -417,7 +418,10 @@ pub type UseCounterCallback = extern "C" fn(&mut Isolate, UseCounterFeature);
 extern "C" {
   static v8__internal__Internals__kIsolateEmbedderDataOffset: int;
 
-  fn v8__Isolate__New(params: *const raw::CreateParams) -> *mut Isolate;
+  fn v8__Isolate__New(
+    group: *const IsolateGroup,
+    params: *const raw::CreateParams,
+  ) -> *mut Isolate;
   fn v8__Isolate__Dispose(this: *mut Isolate);
   fn v8__Isolate__GetNumberOfDataSlots(this: *const Isolate) -> u32;
   fn v8__Isolate__Enter(this: *mut Isolate);
@@ -628,10 +632,10 @@ impl Isolate {
     );
   }
 
-  fn new_impl(params: CreateParams) -> *mut Isolate {
+  fn new_impl(group: &IsolateGroup, params: CreateParams) -> *mut Isolate {
     crate::V8::assert_initialized();
     let (raw_create_params, create_param_allocations) = params.finalize();
-    let cxx_isolate = unsafe { v8__Isolate__New(&raw_create_params) };
+    let cxx_isolate = unsafe { v8__Isolate__New(group, &raw_create_params) };
     let isolate = unsafe { &mut *cxx_isolate };
     isolate.initialize(create_param_allocations);
     cxx_isolate
@@ -642,16 +646,31 @@ impl Isolate {
     self.create_annex(create_param_allocations);
   }
 
-  /// Creates a new isolate.  Does not change the currently entered
+  /// Creates a new isolate. Does not change the currently entered
   /// isolate.
   ///
   /// When an isolate is no longer used its resources should be freed
-  /// by calling V8::dispose().  Using the delete operator is not allowed.
+  /// by calling V8::dispose(). Using the delete operator is not allowed.
   ///
   /// V8::initialize() must have run prior to this.
   #[allow(clippy::new_ret_no_self)]
   pub fn new(params: CreateParams) -> OwnedIsolate {
-    OwnedIsolate::new(Self::new_impl(params))
+    let group = IsolateGroup::get_default();
+    OwnedIsolate::new(Self::new_impl(&group, params))
+  }
+
+  /// Creates a new isolate. Does not change the currently entered
+  /// isolate.
+  ///
+  /// When an isolate is no longer used its resources should be freed
+  /// by calling V8::dispose(). Using the delete operator is not allowed.
+  ///
+  /// V8::initialize() must have run prior to this.
+  pub fn new_with_group(
+    group: &IsolateGroup,
+    params: CreateParams,
+  ) -> OwnedIsolate {
+    OwnedIsolate::new(Self::new_impl(group, params))
   }
 
   #[allow(clippy::new_ret_no_self)]
diff --git a/src/isolate_group.rs b/src/isolate_group.rs
new file mode 100644
index 0000000000..a7261a8239
--- /dev/null
+++ b/src/isolate_group.rs
@@ -0,0 +1,88 @@
+// Copyright 2019-2021 the Deno authors. All rights reserved. MIT license.
+
+use crate::support::Opaque;
+
+#[repr(C)]
+struct InternalIsolateGroup(Opaque);
+
+extern "C" {
+  fn v8__IsolateGroup__GetDefault() -> *const InternalIsolateGroup;
+  fn v8__IsolateGroup__CanCreateNewGroups() -> bool;
+  fn v8__IsolateGroup__Create() -> *const InternalIsolateGroup;
+
+  fn v8__IsolateGroup__DESTRUCT(this: *mut IsolateGroup);
+  fn v8__IsolateGroup__EQ(
+    this: *const IsolateGroup,
+    other: *const IsolateGroup,
+  ) -> bool;
+}
+
+/// The set of V8 isolates in a process is partitioned into groups. Each group
+/// has its own sandbox (if V8 was configured with support for the sandbox) and
+/// pointer-compression cage (if configured with pointer compression).
+///
+/// By default, all isolates are placed in the same group. This is the most
+/// efficient configuration in terms of speed and memory use. However, with
+/// pointer compression enabled, total heap usage of isolates in a group cannot
+/// exceed 4 GB, not counting array buffers and other off-heap storage. Using
+/// multiple isolate groups can allow embedders to allocate more than 4GB of
+/// objects with pointer compression enabled, if the embedder's use case can
+/// span multiple isolates.
+///
+/// Creating an isolate group reserves a range of virtual memory addresses. A
+/// group's memory mapping will be released when the last isolate in the group
+/// is disposed, and there are no more live IsolateGroup objects that refer to
+/// it.
+///
+/// Note that Isolate groups are reference counted, and the IsolateGroup type is
+/// a reference to one.
+///
+/// Note that it's not going to be possible to pass shared JS objects across
+/// IsolateGroup boundary.
+#[repr(C)]
+pub struct IsolateGroup(*const InternalIsolateGroup);
+
+unsafe impl Send for IsolateGroup {}
+unsafe impl Sync for IsolateGroup {}
+
+impl IsolateGroup {
+  /// Return true if new isolate groups can be created at run-time, or false if
+  /// all isolates must be in the same group.
+  pub fn can_create_new_groups() -> bool {
+    unsafe { v8__IsolateGroup__CanCreateNewGroups() }
+  }
+
+  /// Get the default isolate group. If this V8's build configuration only
+  /// supports a single group, this is a reference to that single group.
+  /// Otherwise this is a group like any other, distinguished only in that it is
+  /// the first group.
+  pub fn get_default() -> Self {
+    IsolateGroup(unsafe { v8__IsolateGroup__GetDefault() })
+  }
+
+  /// Create a new isolate group. If this V8's build configuration only supports
+  /// a single group, abort.
+  pub fn create() -> Self {
+    IsolateGroup(unsafe { v8__IsolateGroup__Create() })
+  }
+}
+
+impl Default for IsolateGroup {
+  fn default() -> Self {
+    IsolateGroup::get_default()
+  }
+}
+
+impl Drop for IsolateGroup {
+  fn drop(&mut self) {
+    unsafe { v8__IsolateGroup__DESTRUCT(self) }
+  }
+}
+
+impl Eq for IsolateGroup {}
+
+impl PartialEq for IsolateGroup {
+  fn eq(&self, other: &Self) -> bool {
+    unsafe { v8__IsolateGroup__EQ(self, other) }
+  }
+}
diff --git a/src/lib.rs b/src/lib.rs
index 76db9f790f..3d56a4c9b2 100644
--- a/src/lib.rs
+++ b/src/lib.rs
@@ -48,6 +48,7 @@ mod handle;
 pub mod icu;
 mod isolate;
 mod isolate_create_params;
+mod isolate_group;
 mod microtask;
 mod module;
 mod name;
@@ -126,6 +127,7 @@ pub use isolate::UseCounterCallback;
 pub use isolate::UseCounterFeature;
 pub use isolate::WasmAsyncSuccess;
 pub use isolate_create_params::CreateParams;
+pub use isolate_group::IsolateGroup;
 pub use microtask::MicrotaskQueue;
 pub use module::*;
 pub use object::*;
diff --git a/tests/test_api.rs b/tests/test_api.rs
index 9879983bd0..0558b2850b 100644
--- a/tests/test_api.rs
+++ b/tests/test_api.rs
@@ -630,6 +630,41 @@ fn microtasks() {
   }
 }
 
+#[test]
+fn isolate_groups() {
+  let _setup_guard = setup::parallel_test();
+
+  if !v8::IsolateGroup::can_create_new_groups() {
+    println!("Skipping 'isolate_groups' test: current build does not support isolate groups");
+    return;
+  }
+
+  fn test_isolate_with_group(
+    group: v8::IsolateGroup,
+  ) -> std::thread::JoinHandle<()> {
+    std::thread::spawn(move || {
+      let isolate =
+        &mut v8::Isolate::new_with_group(&group, Default::default());
+      let scope = &mut v8::HandleScope::new(isolate);
+      let context = v8::Context::new(scope, Default::default());
+      let scope = &mut v8::ContextScope::new(scope, context);
+      let result = eval(scope, "1 + 1").unwrap().int32_value(scope).unwrap();
+      assert_eq!(result, 2);
+    })
+  }
+
+  let group1 = v8::IsolateGroup::create();
+  let group2 = v8::IsolateGroup::create();
+
+  let t0 = test_isolate_with_group(Default::default());
+  let t1 = test_isolate_with_group(group1);
+  let t2 = test_isolate_with_group(group2);
+
+  t0.join().unwrap();
+  t1.join().unwrap();
+  t2.join().unwrap();
+}
+
 #[test]
 #[should_panic(
   expected = "v8::OwnedIsolate instances must be dropped in the reverse order of creation. They are entered upon creation and exited upon being dropped."