diff --git a/issue256_test.go b/issue256_test.go
new file mode 100644
index 0000000..96fea69
--- /dev/null
+++ b/issue256_test.go
@@ -0,0 +1,64 @@
+package mergo_test
+
+import (
+	"reflect"
+	"testing"
+
+	"dario.cat/mergo"
+)
+
+func TestIssue256MergeMapCaseInsensitively(t *testing.T) {
+	dst := map[string]map[string]string{
+		"Config": {
+			"Host": "localhost",
+		},
+	}
+	src := map[string]map[string]string{
+		"config": {
+			"host": "example.com",
+			"Port": "443",
+		},
+	}
+
+	if err := mergo.Merge(&dst, src, mergo.WithOverride, mergo.WithCaseInsensitiveMapKeys); err != nil {
+		t.Fatal(err)
+	}
+
+	expected := map[string]map[string]string{
+		"Config": {
+			"Host": "example.com",
+			"Port": "443",
+		},
+	}
+	if !reflect.DeepEqual(dst, expected) {
+		t.Fatalf("got %#v, want %#v", dst, expected)
+	}
+}
+
+func TestIssue256MergeMapCaseInsensitiveWithOverwriteEmpty(t *testing.T) {
+	dst := map[string]string{"Host": "localhost", "User": "root"}
+	src := map[string]string{"host": "example.com"}
+
+	if err := mergo.Merge(&dst, src, mergo.WithOverride, mergo.WithOverwriteWithEmptyValue, mergo.WithCaseInsensitiveMapKeys); err != nil {
+		t.Fatal(err)
+	}
+
+	expected := map[string]string{"Host": "example.com"}
+	if !reflect.DeepEqual(dst, expected) {
+		t.Fatalf("got %#v, want %#v", dst, expected)
+	}
+}
+
+func TestIssue256MergeMapCaseSensitiveByDefault(t *testing.T) {
+	dst := map[string]string{"Host": "localhost"}
+	src := map[string]string{"host": "example.com"}
+
+	if err := mergo.Merge(&dst, src, mergo.WithOverride); err != nil {
+		t.Fatal(err)
+	}
+
+	expected := map[string]string{"Host": "localhost", "host": "example.com"}
+	if !reflect.DeepEqual(dst, expected) {
+		t.Fatalf("got %#v, want %#v", dst, expected)
+	}
+}
diff --git a/merge.go b/merge.go
index 5488338..4f0182a 100644
--- a/merge.go
+++ b/merge.go
@@ -11,6 +11,7 @@ package mergo
 import (
 	"fmt"
 	"reflect"
+	"strings"
 )
 
 func hasMergeableFields(dst reflect.Value) (exported bool) {
@@ -46,6 +47,7 @@ type Config struct {
 	overwriteWithEmptyValue      bool
 	overwriteSliceWithEmptyValue bool
 	sliceDeepCopy                bool
+	caseInsensitiveMapKeys       bool
 }
 
 type Transformers interface {
@@ -116,16 +118,26 @@ func deepMerge(dst, src reflect.Value, visited map[uintptr]*visit, depth int, co
 		}
 
 		for _, key := range src.MapKeys() {
+			mergeKey := key
+			if config.caseInsensitiveMapKeys && key.Kind() == reflect.String && dst.Type().Key().Kind() == reflect.String {
+				for _, dstKey := range dst.MapKeys() {
+					if strings.EqualFold(dstKey.String(), key.String()) {
+						mergeKey = dstKey
+						break
+					}
+				}
+			}
+
 			srcElement := src.MapIndex(key)
 			if !srcElement.IsValid() {
 				continue
 			}
-			dstElement := dst.MapIndex(key)
+			dstElement := dst.MapIndex(mergeKey)
 			switch srcElement.Kind() {
 			case reflect.Chan, reflect.Func, reflect.Map, reflect.Interface, reflect.Slice:
 				if srcElement.IsNil() {
 					if overwrite {
-						dst.SetMapIndex(key, srcElement)
+						dst.SetMapIndex(mergeKey, srcElement)
 					}
 					continue
 				}
@@ -190,7 +202,7 @@ func deepMerge(dst, src reflect.Value, visited map[uintptr]*visit, depth int, co
 						}
 
 					}
-					dst.SetMapIndex(key, dstSlice)
+					dst.SetMapIndex(mergeKey, dstSlice)
 				}
 			}
 
@@ -207,7 +219,7 @@ func deepMerge(dst, src reflect.Value, visited map[uintptr]*visit, depth int, co
 				if dst.IsNil() {
 					dst.Set(reflect.MakeMap(dst.Type()))
 				}
-				dst.SetMapIndex(key, srcElement)
+				dst.SetMapIndex(mergeKey, srcElement)
 			}
 		}
 
@@ -215,6 +227,14 @@ func deepMerge(dst, src reflect.Value, visited map[uintptr]*visit, depth int, co
 		if overwriteWithEmptySrc {
 			for _, key := range dst.MapKeys() {
 				srcElement := src.MapIndex(key)
+				if !srcElement.IsValid() && config.caseInsensitiveMapKeys && key.Kind() == reflect.String && src.Type().Key().Kind() == reflect.String {
+					for _, srcKey := range src.MapKeys() {
+						if strings.EqualFold(srcKey.String(), key.String()) {
+							srcElement = src.MapIndex(srcKey)
+							break
+						}
+					}
+				}
 				if !srcElement.IsValid() {
 					dst.SetMapIndex(key, reflect.Value{})
 				}
@@ -367,6 +387,11 @@ func WithSliceDeepCopy(config *Config) {
 	config.Overwrite = true
 }
 
+// WithCaseInsensitiveMapKeys will make merge match string map keys case-insensitively.
+func WithCaseInsensitiveMapKeys(config *Config) {
+	config.caseInsensitiveMapKeys = true
+}
+
 func merge(dst, src interface{}, opts ...func(*Config)) error {
 	if dst != nil && reflect.ValueOf(dst).Kind() != reflect.Ptr {
 		return ErrNonPointerArgument